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Mechanistically, siNrf2 transfection reverses these effects, indicating that Nrf2 mediates the proapoptotic effects of Res on fibroblast-like synoviocytes

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Andrea Maier, a professor of medicine at the National University of Singapore who runs the Chi Longevity Clinic at the Four Seasons there, said that the clinical evidence simply isn't there yet for a lot of these peptides